1.西湖大学合成生物学与生物智造中心,浙江 杭州,310030
2.浙江省全省智能低碳生物合成重点实验室,浙江 杭州,310030
3.西湖大学工学院合成生物学与生物工程实验室,浙江 杭州,310030
曾安平(1963—),男,德国工程院院士,西湖大学合成生物学与生物工程讲席教授,博士生导师。研究方向为合成生物学及生物制造,生物化工,生物医药与健康;研究重点为细胞工厂构建,CO2等一碳化合物生物转化、电驱动生物技术及其应用、智能生物材料及能量代谢分子等。
收稿:2026-05-08,
修回:2026-05-31,
网络首发:2026-06-02,
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曾安平, 马成伟, 关傲聪, 聂晶磊, 李昕, 战春君, 刘建明. 城市智能代谢及生物制造体系:重塑未来城市生态与绿色经济[J]. 合成生物学, 2026, 7. DOI: 10.12211/2096-8280.2026-040
ZENG Anping, MA Chengwei, GUAN Aocong, NIE Jinglei, LI Xin, ZHAN Chunjun, LIU Jianming. Urban intelligent metabolism and biomanufacturing system: reshaping the future of urban ecology and green economy[J]. Synthetic Biology Journal, 2026, 7. DOI: 10.12211/2096-8280.2026-040
曾安平, 马成伟, 关傲聪, 聂晶磊, 李昕, 战春君, 刘建明. 城市智能代谢及生物制造体系:重塑未来城市生态与绿色经济[J]. 合成生物学, 2026, 7. DOI: 10.12211/2096-8280.2026-040 DOI:
ZENG Anping, MA Chengwei, GUAN Aocong, NIE Jinglei, LI Xin, ZHAN Chunjun, LIU Jianming. Urban intelligent metabolism and biomanufacturing system: reshaping the future of urban ecology and green economy[J]. Synthetic Biology Journal, 2026, 7. DOI: 10.12211/2096-8280.2026-040 DOI:
“十五五”时期,我国推进现代化产业体系的重要目标之一是实现经济社会的全面绿色转型。生物制造因原料可持续、加工过程绿色、产业潜力巨大,被四中全会再次强调为高技术绿色发展的未来关键产业。目前,生物制造主要应用于医药、化工、能源、材料、农业和食品领域,但其大规模应用受限于原料和能源供给。绿色能源转型同样是“十五五”的重要目标,但存在如何解决“发得出、接得住、用得好”的难题。另一方面,我国城市化发展迅速, 面临环境、就业和空间结构等多重压力。生物制造与绿色能源、城市化融合,可拓展应用边界、优化能源利用,同时缓解城市生态,人口就业压力,为绿色智慧城市和城市工业提供动力,加速生产生活方式的绿色低碳转型。因此,我们提出建设“城市智能代谢及生物制造体系”,打造了其技术示范空间,作为未来城市生活与社会经济绿色低碳发展的新范式。本文将介绍该体系的背景与核心内容,综述其关键技术,并以千万人口城市为例,展示通过构建城市智造代谢空间,每年可形成千亿元规模的就地生产,就地消费的城市生物制造产业。依托生物制造,未来城市将成为兼顾高效空间利用、零碳经济发展、就业提升与宜居舒适的“智能代谢空间”。
During the 15th Five-Year Plan period
one of China's key objectives in building a modern industrial system is to achieve a comprehensive green transformation of the economy and society. Biomanufacturing
recognized for its sustainable feedstocks
green processing
and significant industrial potential
has been reaffirmed as a future-oriented key industry for high-tech green development in China. Currently
biomanufacturing is primarily applied in the areas of pharmaceuticals
chemicals
energy
materials
agriculture
and food
yet its large-scale deployment remains constrained by feedstock and energy supply. The green energy transition is another major goal of the 15th Five-Year Plan
but it faces challenges in effectively matching "generation
storage
and utilization." Meanwhile
rapid urbanization in China has intensified pressures on the environment
employment
and spatial layout. The integration of biomanufacturing with green energy and urbanization could expand the application scope of biomanufacturing
optimize energy use
and simultaneously alleviate urban ecological and employment pressures
thereby revitalizing green smart cities and urban industries and accelerating the green and low-carbon transformation of production and lifestyles. To this end
we propose the concept of an "Urban Intelligent Metabolism and Biomanufacturing System" as a new paradigm for the green and low-carbon development of future urban life and socio-economic activities. This article introduces the background and core elements of this system
reviews its key technologies
and illustrates how constructing an urban intelligent "metabolic space" in a megacity could generate a locally produced and consumed biomanufacturing industry worth hundreds of billions of RMB annually. Leveraging biomanufacturing
future cities are envisioned as "intelligent metabolic spaces" that combine efficient space utilization
zero-carbon economic growth
enhanced employment
and livability.
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