Dry biorefining production of straw sugar from wheat straw feedstock and its techno-economic assessment

HAN Tao; XIANG Zhiqiang; UMUTUMWA Eric Principe; ZHANG Bin; BAO Jie

doi:10.12211/2096-8280.2026-054

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Dry biorefining production of straw sugar from wheat straw feedstock and its techno-economic assessment

更新时间：2026-09-18

- Dry biorefining production of straw sugar from wheat straw feedstock and its techno-economic assessment
- 秸秆糖的干法生物炼制生产及其技术经济性评价
- Synthetic Biology Journal Pages: 1-25(2026)
- 作者机构：
  
  华东理工大学生物工程学院生物反应器工程全国重点实验室，上海 200237
- 作者简介：
- 基金信息：
- DOI：10.12211/2096-8280.2026-054
  CLC： Q819
- Received：09 June 2026，
  
  Revised：2026-09-16，
  
  Online First：18 September 2026，
- 稿件说明：
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韩涛，向志强， UMUTUMWA Eric Principe，张斌，鲍杰. 秸秆糖的干法生物炼制生产及其技术经济性评价［J］. 合成生物学， 2026， 7. DOI： 10.12211/2096-8280.2026-054

HAN Tao， XIANG Zhiqiang， UMUTUMWA Eric Principe， ZHANG Bin， BAO Jie. Dry biorefining production of straw sugar from wheat straw feedstock and its techno-economic assessment［J］. Synthetic Biology Journal， 2026， 7. DOI： 10.12211/2096-8280.2026-054
韩涛，向志强， UMUTUMWA Eric Principe，张斌，鲍杰. 秸秆糖的干法生物炼制生产及其技术经济性评价［J］. 合成生物学， 2026， 7. DOI： 10.12211/2096-8280.2026-054 DOI：

HAN Tao， XIANG Zhiqiang， UMUTUMWA Eric Principe， ZHANG Bin， BAO Jie. Dry biorefining production of straw sugar from wheat straw feedstock and its techno-economic assessment［J］. Synthetic Biology Journal， 2026， 7. DOI： 10.12211/2096-8280.2026-054 DOI：

摘要

糖是生物制造和合成生物产业的核心原料和物质基础。来自玉米原料的淀粉糖体量远不足以支撑未来大规模生物制造和合成生物学产业所需糖原料的体量。通过生物炼制技术从木质纤维素类非粮生物质（如农作物秸秆）生产秸秆糖是未来最重要的出路之一。目前常规生物炼制技术存在着大量有毒废水排放、低转化指标、高化石能源消耗等重大技术障碍。本文以突破上述关键技术障碍为目标，通过干法预处理、低酶糖化、液态生物脱毒等步骤构成的干法生物炼制技术为过程平台，对零废水/零抑制物排放、过程能量自给以及低水耗、低腐蚀、长期储存等因素限制下的秸秆糖过程技术和技术经济性进行了深入研究。对以麦秆为原料的干法生物炼制技术生产秸秆糖的转化、排放、能耗等指标，以及发酵性能、稳定性、可运输性等各方面进行了实验研究；以年加工5万吨（干重）麦秆原料生产秸秆糖的干法生物炼制过程为案例进行了技术经济性分析。结果表明，干法生物炼制生产秸秆糖在转化、排放、能耗、成本等各项可量化指标方面与玉米干法加工生产葡萄糖基本一致，而生产成本仅为淀粉糖的一半。本研究为非粮生物质为原料进行大宗生物基化学品的低碳制造提供了可规模化供应的糖原料平台，也为合成生物学研究提出了丰富的科学问题，并极大拓展了其研究领域。

Abstract

Sugar serves as the core raw material and material foundation of the biomanufacturing industry

and also constitutes the essential carbon source and energy supply for the growth of downstream cell factories in synthetic biology and their conversion to target products. Starch-derived sugars from corn-based feedstocks are far from sufficient to meet the demand for sugar feedstocks required by future large‑scale biomanufacturing and the industrialization of synthetic biology. The production of straw sugar from lignocellulosic non‑food biomass (e.g.

crop straw) via biorefinery technologies represents one of the most promising pathways forward. However

current conventional biorefinery technologies face major technical obstacles

including the discharge of large volumes of toxic wastewater

low conversion performance

and high fossil energy consumption. Aiming to overcome these key technical barriers

this study employs a dry biorefining technology platform consisting of dry pretreatment

low‑enzyme saccharification

and liquid‑phase biodetoxification steps to conduct an in‑depth investigation into the process technology and techno‑economics of straw sugar production under the constraints of zero wastewater/inhibitor discharge

process energy self‑sufficiency

low water consumption

low corrosiveness

and long‑term storage. Experimental studies were carried out on the conversion

emission

and energy consumption metrics

as well as the fermentation performance

stability

and transportability of straw sugar produced via the dry biorefining technology using wheat straw as the feedstock. A techno‑economic analysis was performed based on a case study of a dry biorefining process with an annual processing capacity of 50

000 metric tons (dry weight) of wheat straw for straw sugar production. The results show that all quantifiable metrics—including conversion

emissions

energy consumption

and cost—of straw sugar production via dry biorefining are essentially consistent with those of glucose production via dry corn processing

while the production cost is only half that of starch sugars. This study establishes a scalable sugar feedstock platform for the low‑carbon production of bulk bio‑based chemicals from non‑food biomass. In addition

it raises a wealth of scientific questions for synthetic biology research and significantly expands the frontiers of this field.

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Keywords

references

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