The current advance in artificial chromosome based DNA information storage

YANG Yang; FAN Chunhai

doi:10.12211/2096-8280.2021-043

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The current advance in artificial chromosome based DNA information storage

Comment | 更新时间：2025-03-20

- The current advance in artificial chromosome based DNA information storage
- Synthetic Biology Journal Vol. 2, Issue 3, Pages: 305-308(2021)
- 作者机构：
  
  1.上海交通大学医学院附属仁济医院，分子医学研究院，上海 200127
  2.上海交通大学化学化工学院，上海 200240
- 作者简介：
- 基金信息：
- DOI：10.12211/2096-8280.2021-043
  CLC： Q819
- Received：09 April 2021，
  
  Revised：2021-04-21，
  
  Published：30 June 2021
- 稿件说明：
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杨洋，樊春海. 基于人工染色体的DNA信息存储前沿进展［J］. 合成生物学， 2021， 2（3）： 305-308

YANG Yang， FAN Chunhai. The current advance in artificial chromosome based DNA information storage［J］. Synthetic Biology Journal， 2021， 2（3）： 305-308
杨洋，樊春海. 基于人工染色体的DNA信息存储前沿进展［J］. 合成生物学， 2021， 2（3）： 305-308 DOI： 10.12211/2096-8280.2021-043.

YANG Yang， FAN Chunhai. The current advance in artificial chromosome based DNA information storage［J］. Synthetic Biology Journal， 2021， 2（3）： 305-308 DOI： 10.12211/2096-8280.2021-043.

摘要

作为信息存储的替代材料，DNA体现着高信息存储密度和长期稳定等特性。来自天津大学的元英进教授团队最近在酵母菌内完成了从头设计并合成一条人工染色体用于编码两张图片和一段视频数据的研究。这项成果建立了体内组装编码的人工染色体的数据存储策略，可以实现一次写入、稳定复制和多次读取，从而体现出低成本海量数据分发的巨大优势。

Abstract

DNA offers an alternative material for digital storage with high information density and long-term stability. A

de novo

design and synthesis of an artificial chromosome that encodes two pictures and a video clip has recently been achieved by Prof. Yingjin Yuan's group from Tianjin University

Tianjin

China. This study establishes a data storage strategy using encoded artificial chromosomes

via in

vivo

assembly. It allows multiple retrievals from a onetime written and stable replication

which advances in the economically massive data distribution.

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Keywords

references

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上海交通大学医学院附属仁济医院，分子医学研究院

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