Recent advances in plant synthetic biology

ZHANG Bo; MA Yongshuo; SHANG Yi; HUANG Sanwen

doi:10.12211/2096-8280.2020-016

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Recent advances in plant synthetic biology

Invited Review | 更新时间：2025-03-20

- Recent advances in plant synthetic biology
- Synthetic Biology Journal Vol. 1, Issue 2, Pages: 121-140(2020)
- 作者机构：
  
  1.云南师范大学马铃薯科学研究院,云南省马铃薯生物学重点实验室，云南昆明 650500
  2.中国农业科学院农业基因组研究所，农业部基因组分析重点实验室，广东省岭南现代农业实验室，广东深圳 518120
  3.麻省理工学院化学工程系，马萨诸塞州剑桥市，02139
- 作者简介：
- 基金信息：
- DOI：10.12211/2096-8280.2020-016
  CLC： Q81
- Received：04 March 2020，
  
  Revised：2020-04-09，
  
  Published：30 April 2020
- 稿件说明：
移动端阅览
张博, 马永硕, 尚轶, 黄三文. 植物合成生物学研究进展[J]. 合成生物学, 2020, 1(2): 121-140

ZHANG Bo, MA Yongshuo, SHANG Yi, HUANG Sanwen. Recent advances in plant synthetic biology[J]. Synthetic Biology Journal, 2020, 1(2): 121-140
张博, 马永硕, 尚轶, 黄三文. 植物合成生物学研究进展[J]. 合成生物学, 2020, 1(2): 121-140 DOI： 10.12211/2096-8280.2020-016.

ZHANG Bo, MA Yongshuo, SHANG Yi, HUANG Sanwen. Recent advances in plant synthetic biology[J]. Synthetic Biology Journal, 2020, 1(2): 121-140 DOI： 10.12211/2096-8280.2020-016.

摘要

合成生物学是汇聚了工程学和生物学的新兴交叉学科，近年来逐步在植物研究领域中显现其重要作用。利用合成生物学技术不仅可以对作物的产量及营养品质性状进行精准的改良和优化，还有望将植物改造成高价值的植物天然产物生产工厂满足人们更多的需求。本文从DNA合成与组装、植物基因编辑技术、核和质体遗传转化体系以及染色体工程等方面介绍了在植物中广泛应用的合成生物学技术。阐述了利用合成生物学开展多样化生物传感器设计、作物产量优化、营养品质强化、植物天然产物与蛋白高效合成等方面的最新研究进展。最后讨论了目前植物合成生物学所面临的问题以及今后的发展趋势。相信经过新一轮的快速发展，植物合成生物学将在未来农作物育种中发挥越来越重要的作用。

Abstract

Synthetic biology is a new interdisciplinary field that combines engineering and biology. With an initial focus on microbial systems

it is now increasingly developed for plants. Plant synthetic biology has been applied to design crops for improved yield and nutritional value. It is also possible to transform plants into living factories for producing high-value natural products. In this review

we first summarize the definition of plant synthetic biology and introduce emerging technologies

including DNA synthesis and assembly

genome editing

genetic transformation targeting nucleus and plastid

and chromosome engineering. We then discuss recent applications in biosensor design

yield and nutrition improvement

and natural product and protein biosynthesis. We conclude with the current challenges and future perspective of this field. We envision plant synthetic biology will revolutionize crop breeding.

关键词

Keywords

references

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