生物制造的市本率（PC值）：定义与应用

张以恒; 陈雪梅; 石婷

doi:10.12211/2096-8280.2024-072

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生物制造的市本率（PC值）：定义与应用

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- 生物制造的市本率（PC值）：定义与应用
- Price to Cost-of-raw-materials Ratio (PC) of biomanufacturing: definition and application
- 合成生物学 2025年6卷第1期页码：8-17
- 作者机构：
  
  1.中国科学院天津工业生物技术研究所，低碳合成工程生物学全国重点实验室，天津 300308
  2.中国科学院天津工业生物技术研究所，体外合成生物学中心，天津 300308
  3.国家合成生物技术创新中心，天津 300308
- 作者简介：
  
  [ "张以恒（1971—），男，研究员，博士生导师，低碳合成工程生物学全国重点实验室主任，中国科学院天津工业生物技术研究所体外合成生物学中心主任。创建体外生物转化（ivBT）技术平台，设计与构建多酶分子机器。在秸秆制粮、人工呼吸作用（糖水产氢）、健康糖与肌醇合成等生物制造领域取得了一系列原创性突破。 E-mail：zhang_xw@tib.cas.cn" ]
- 基金信息：
  
  国家重点研发计划“合成生物学”重点专项(2022YFA0912303);国家自然科学基金面上项目(NSFC 32271544);合成生物学海河实验室颠覆性创新项目(22HHSWSS000155);天津市合成生物技术创新能力提升行动项目(TSBICIP-CXRC-067)
- DOI：10.12211/2096-8280.2024-072
  中图分类号： Q81
- 收稿：2024-09-18，
  
  修回：2024-11-26，
  
  纸质出版：2025-01-31
- 稿件说明：
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张以恒，陈雪梅，石婷. 生物制造的市本率（PC值）：定义与应用［J］. 合成生物学， 2025， 6（1）： 8-17

ZHANG Yi-Heng P. Job， CHEN Xuemei， SHI Ting. Price to Cost-of-raw-materials Ratio （PC） of biomanufacturing： definition and application［J］. Synthetic Biology Journal， 2025， 6（1）： 8-17
张以恒，陈雪梅，石婷. 生物制造的市本率（PC值）：定义与应用［J］. 合成生物学， 2025， 6（1）： 8-17 DOI： 10.12211/2096-8280.2024-072.

ZHANG Yi-Heng P. Job， CHEN Xuemei， SHI Ting. Price to Cost-of-raw-materials Ratio （PC） of biomanufacturing： definition and application［J］. Synthetic Biology Journal， 2025， 6（1）： 8-17 DOI： 10.12211/2096-8280.2024-072.

摘要

生物制造是中国“十四五”战略性新兴产业之一。本文作者曾经提出“道法术器”对工业生物制造的哲学指导意义。为了深入阐述生物制造中“法以立本”的原则，本文首次提出“市本率”这一创新性概念，即产品市场价格与原料成本的比值，英文全称是Price to Cost-of-raw-materials Ratio，简称PC值。市本率是一个衡量技术水平与经济价值的关键指标，具有简单、公开、透明的属性，提供了生物制造产品分类新方法，有助于指导新技术增效和降本的发展路径，预判生物产品未来制造成本及市场价格的趋势，评估新兴生物技术的产业化潜力。市本率的计算与分析，作为一种新方法学工具，将为生物制造战略新兴产业的未来发展提供顶层设计的新视角，深化对生物制造产品市场前景的理解，推动生物经济高质量发展。

Abstract

Biomanufacturing is one of the strategic emerging industries in China during the “14th Five-Year Plan” period. The author once proposed “Tao-Fa-Shu-Qi” for the industrial biomanufacturing and provided its philosophical guideline. Focusing on the “Fa” of biological manufacturing and further analyzing the concept of “Fa as rules” in biomanufacturing

the author first proposed the concept of “Price to Cost-of-raw-materials Ratio” (PC value)

which is the ratio of product market price to cost with raw materials. Biomanufactured products can be categorized by PC value into high-value products

value-added products

biocommodity

and products for public good. The PC value is a key indicator for evaluating the technological capability and economic viability of biomanufactured products. It is simple

transparent

and publicly accessible

offering a new approach for categorizing biomanufactured products. This indicator aids in guiding new technologies towards pathways of efficiency enhancement and cost reduction

forecasting future manufacturing costs and market prices for bioproducts

and assessing the industrialization potential of emerging biotechnologies. This article focuses on the biomanufacturing of fructose syrup

fructose solution

crystalline fructose

allulose

myo-inositol

and tagatose as examples

analyzing pathways for developing new technologies and predicting their economic feasibility. The calculation and analysis of the PC value could provide a new methodological tool for the top-level strategic design of the future development of emerging biomanufacturing industries

and could effectively facilitate the high-quality development of the bioeconomy.

关键词

Keywords

references

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